1Place the chicken breast fillets in a bowl and pour the buttermilk over them. Cover and refrigerate for at least 1 hour.
In a shallow dish, combine the flour, paprika, garlic powder, onion powder, salt, black pepper, and cayenne pepper.
Heat the vegetable oil in a large skillet over medium-high heat.
Remove the chicken from the buttermilk, allowing any excess to drip off. Dredge each fillet in the flour mixture, ensuring they are well coated.
Carefully place the coated chicken fillets in the hot oil and fry for about 5-7 minutes on each side, or until golden brown and cooked through.
Remove the chicken from the oil and place on a paper towel-lined plate to drain any excess oil.
Toast the hamburger buns lightly.
Assemble the sandwiches by placing a fried chicken fillet on the bottom half of each bun. Top with a lettuce leaf and a tomato slice, then cover with the top half of the bun.
Serve immediately and enjoy your Southern Fried Chicken Sandwich!